An eight months old female child was brought to pediatric OPD with complaints of fever and recurrent ear discharge. On examination, there was otitis media and also lower respiratory tract infection. The weight of the child was below its age group. The mother gave a similar history to her elder son during infancy. The physician advised quantitative evaluation of serum Immunoglobulins, and prescribed antibiotics and antipyretics, and assured the mother that child will spontaneously recover after the age of 2-6 years.
What is probable immunodeficiency disorder in this child?
Immunodeficiency disorder may be transient hypogamma globulinemia.
ReplyDeleteIn this disease , delayed maturation & onset of normal IgG synthesis occur.
Due to decreased immunity , there is more chances of recurrent infection such as otitis media, and Loer respiratory tract infection as in patient.
This disorder can resolve after the age of 2-6 yrs.
good.
DeleteTransient hypogammaglobulinemia of infancy (THI) is a primary immunodeficiency caused by a transitory drop of the levels of immunoglobulin G (IgG) in an infant beginning between 5 and 24 months of age. Levels typically return to reference range at ages 2 to 6 years.
ReplyDeleteThese levels usually increase to the reference range by age 2–6 years in children with THI.
ReplyDeleteAreeba Khan
Roll no 16
Daignosis-
Immunodeficiencyy disorder may be transient hypogamma globulinemia.
In this disease , delayed maturation & onset of normal IgG synthesis occur.
Due to decreased immunity , there is more chances of recurrent infection such as otitis media, and Loer respiratory tract infection as in patient.
This disorder can resolve after the age of 2-6 yrs.
Transient hypogammaglobulinemia of infancy (THI) is a primary immunodeficiency caused by a transitory drop of the levels of immunoglobulin G (IgG) in an infant beginning between 5 and 24 months of age. Levels typically return to reference range at ages 2 to 6 years.
ReplyDeleteThese levels usually increase to the reference range by age 2–6 years in children with THI.
Shruti Chauhan
Roll no.79
Name: HIFZA NAFIS
ReplyDeleteRoll number: 34
The probable immunodeficiency disorder in the child can be TRANSIENT HYPOGAMMA GLOBULINEMIA.
Transient hypogammaglobulinemia of infancy (THI) is a transitory immunodeficiency of childhood characterized by low IgG levels.
THI typically presents during the first year of life with recurrent upper and lower respiratory tract infections.
Atopy is a common manifestation.
The primary differential diagnoses include X-linked agammaglobulinemia and common variable immunodeficiency.
The diagnosis of THI confirmed retrospectively when IgG levels have returned to expected levels.
Transient hypogamma globulinemia
ReplyDeleteCan be resolved after 2-6 years of age.caused by transient drop in immunoglobulin g in infants ageing between 5montha to 24 months.secondsry infection due to decreased immunity.
Transient hypogammaglobulinemia of infancy (THI) is a primary immunodeficiency caused by a transitory drop of the levels of immunoglobulin G (IgG) in an infant beginning between 5 and 24 months of age. Levels typically return to reference range at ages 2 to 6 years.
ReplyDeleteThese levels usually increase to the reference range by age 2–6 years in children with THI.
Vaishnavi sharma
94
Anand kumar
ReplyDeleteRoll n.07
Transient hypogamma globulinemia
Delayed maturation and onset of normal IgG synthesis occurs
due to decreased immunity ,there is more chances of recurrent infection such as otitis media and lower respiratory tract infection as in patient. this disorder can resolve after the age of 2-6 years
Daignosis-
ReplyDeleteImmunodeficiencyy disorder may be transient hypogamma globulinemia.
In this disease , delayed maturation & onset of normal IgG synthesis occur.
Due to decreased immunity , there is more chances of recurrent infection such as otitis media, and Loer respiratory tract infection as in patient.
This disorder can resolve after the age of 2-6 yrs.
Vaishnavi sharma
94
TRANSIENT HYPOGAMMA GLOBULINEMIA.
ReplyDeleteTransient hypogammaglobulinemia of infancy (THI) is a transitory immunodeficiency of childhood characterized by low IgG levels.
THI typically presents during the first year of life with recurrent upper and lower respiratory tract infections.
Atopy is a common manifestation.
The primary differential diagnoses include X-linked agammaglobulinemia and common variable immunodeficiency.
Transient hypogammaglobulenemia of infancy
ReplyDelete*abnormal delay in initiation of IgE synthesis in some infants.
*maternal IgE is slowly catabolised in newborn and reaches 200mg/100 ml by 2 nd month.
*delay in synthesis of its own IgE by this age, immunodeficiency occurs.
*infants of both sexes
*recurrent otitis media and respiratory infections
Harsh Tiwari
ReplyDeleteRoll No 32
Transient hypogammaglobulinemia of infacy
*primary immunodeficiency caused by a transitory drop of level of IgE in infants beginning between 5-24 months of age.
*symptoms- recurrent sinopulmonary or GI infection, candidasis, and sometimes meningitis
Transient hypogammaglobulinemia of infancy (THI) is a primary immunodeficiency caused by a transitory drop of the levels of immunoglobulin G (IgG) in an infant beginning between 5 and 24 months of age. Levels typically return to reference range at ages 2 to 6 years.
ReplyDeleteThese levels usually increase to the reference range by age 2–6 years in children with THI.
Name-Mohd Maaz
Roll no-49
hypogammaglobulinemia of infancy
ReplyDeleteThis occurs due to an abnormal delay in the initiation of synthesis lgG (or some time IgA or IgM)
lgG synthesis usually starts by 2 months of age. But in some infants, it is delayed leading to defect in opsonization or complement activation resulting in recurrent otitis media and respiratory infections.
Immunodeficiency disorder may be transient hypogamma globinemia.
ReplyDeleteCaused due to drop in level of immunoglobulin G(IgG)
In an infant.
Decreased immunity there is more chances of recurrent infection such as otitis media and lower respiratory tract infection.
Immunodeficiency disorder may be Transient hypogammaglobulinemia of infancy (THI) is a primary immunodeficiency caused by a transitory drop of the levels of immunoglobulin G (IgG) in an infant beginning between 5 and 24 months of age.
ReplyDeleteLevels typically return to reference range at ages 2 to 6 years. IgG is produced at low levels by the fetus, and it is the only immunoglobulin to cross the placenta.Due to decreased immunity, there is more chances of recurrent infection such as otitis media, can lower respiratory tract infection patient. This disorder can resolve after 2- 6 years
Aryaman singh
ReplyDeleteRoll no 18
Transient hypogamma globulinemia
Delayed maturation and onset of normal IgG synthesis occurs
due to decreased immunity ,there is more chances of recurrent infection such as otitis media and lower respiratory tract infection as in patient. this disorder can resolve after the age of 2-6 years
ReplyDeleteSAMRIDDHi GUPTA
ROLL NO. 71
Immunodeficiency disorder may be transient hypogamma globulinemia.
In this disease , delayed maturation & onset of normal IgG synthesis occur.
Due to decreased immunity , there is more chances of recurrent infection such as otitis media, and Loer respiratory tract infection as in patient.
This disorder can resolve after the age of 2-6 yrs.
Transient hypogammaglobulenemia of infancy
ReplyDelete*abnormal delay in initiation of IgE synthesis in some infants. *maternal IgE is slowly catabolised in newborn and reaches 200mg/100 ml by 2 nd month.
*delay in synthesis of its own IgE by this age, immunodeficiency occurs.
*infants of both sexes
*recurrent otitis media and respiratory infections
Nitin Gupta
Roll No-56
immunodeficiency disorder may be transient hypogamma globulinemia.
ReplyDeleteIn this disease , delayed maturation & onset of normal IgG synthesis occur.
Due to decreased immunity , there is more chances of recurrent infection such as otitis media, and Loer respiratory tract infection as in patient.
This disorder can resolve after the age of 2-6 yrs.
ANUBHAV AGRAHARI
ROLL-NO15
Daignosis-
ReplyDeleteImmunodeficiencyy disorder may be transient hypogamma globulinemia.
In this disease , delayed maturation & onset of normal IgG synthesis occur.
Due to decreased immunity , there is more chances of recurrent infection such as otitis media, and Loer respiratory tract infection as in patient.
This disorder can resolve after the age of 2-6 yrs.
Diksha(24)
Immunodeficiency disorder -transient hypogammaglobulinemia
ReplyDeleteDelayed maturation and onset of normal IG synthesis occur
Here due to decreased immunity there is more chances of infection to occur such as otitis media and lower respiratory tract infection occurs
This disorder can be resolved after 2-6 years
Anupriya
ReplyDeleteRollno.14
It is a case of primary immunodeficiency disorder . Characterized by decreased level of serum IgG levels . Due to decreased immunity chance of recurrent infections increase in body.
hypogammaglobulinemia of infancy
ReplyDeleteThis occurs due to an abnormal delay in the initiation of synthesis lgG (or some time IgA or IgM)
lgG synthesis usually starts by 2 months of age. But in some infants, it is delayed leading to defect in opsonization or complement activation resulting in recurrent otitis media and respiratory infections.
Shreya
77
Sakshi
ReplyDeleteRoll no.68
Probable diagnosis in this child is transient hypogammaglobinemia of infancy (THI).
it occurs because there is decreased level of IgG in infant during 5 to 24 months of age. Hence there are recurrent infections. This disorder resolves after age of 2-6 yrs of age when IgG level increases to reference range.
Amit Maddheshiya
ReplyDeleteRill no. 06
Immunodeficiencyy disorder may be transient hypogamma globulinemia.
This occurs due to an abnormal delay in the initiation of synthesis lgG (or some time IgA or IgM)
lgG synthesis usually starts by 2 months of age. But in some infants, it is delayed leading to defect in opsonization or complement activation resulting in recurrent otitis media and respiratory infections.